Chargement en cours...
Chemo‐Enzymatic Modification of the 5′ Cap Maintains Translation and Increases Immunogenic Properties of mRNA
Eukaryotic mRNAs are emerging modalities for protein replacement therapy and vaccination. Their 5′ cap is important for mRNA translation and immune response and can be naturally methylated at different positions by S‐adenosyl‐l‐methionine (AdoMet)‐dependent methyltransferases (MTases). We report on...
Enregistré dans:
| Publié dans: | Angew Chem Int Ed Engl |
|---|---|
| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
John Wiley and Sons Inc.
2021
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8250829/ https://ncbi.nlm.nih.gov/pubmed/33751748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202100352 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|