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Photocaged 5′ cap analogues for optical control of mRNA translation in cells

The translation of messenger RNA (mRNA) is a fundamental process in gene expression, and control of translation is important to regulate protein synthesis in cells. The primary hallmark of eukaryotic mRNAs is their 5′ cap, whose molecular contacts to the eukaryotic translation initiation factor eIF4...

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Bibliografiske detaljer
Udgivet i:Nat Chem
Main Authors: Klöcker, Nils, Weissenboeck, Florian P., van Dülmen, Melissa, Špaček, Petr, Hüwel, Sabine, Rentmeister, Andrea
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2022
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7613264/
https://ncbi.nlm.nih.gov/pubmed/35725774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41557-022-00972-7
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