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Photocaged 5′ cap analogues for optical control of mRNA translation in cells

The translation of messenger RNA (mRNA) is a fundamental process in gene expression, and control of translation is important to regulate protein synthesis in cells. The primary hallmark of eukaryotic mRNAs is their 5′ cap, whose molecular contacts to the eukaryotic translation initiation factor eIF4...

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Detalhes bibliográficos
Publicado no:Nat Chem
Main Authors: Klöcker, Nils, Weissenboeck, Florian P., van Dülmen, Melissa, Špaček, Petr, Hüwel, Sabine, Rentmeister, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2022
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7613264/
https://ncbi.nlm.nih.gov/pubmed/35725774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41557-022-00972-7
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