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Phosphoinositide 3-Kinase p110 Delta Differentially Restrains and Directs Naïve Versus Effector CD8(+) T Cell Transcriptional Programs
Phosphoinositide 3-kinase p110 delta (PI3K p110δ) is pivotal for CD8(+) T cell immune responses. The current study explores PI3K p110δ induction and repression of antigen receptor and cytokine regulated programs to inform how PI3K p110δ directs CD8(+) T cell fate. The studies force a revision of the...
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| Опубликовано в: : | Front Immunol |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Frontiers Media S.A.
2021
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8250422/ https://ncbi.nlm.nih.gov/pubmed/34220851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.691997 |
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