The RNA sensor MDA5 detects SARS-CoV-2 infection

Human cells respond to infection by SARS-CoV-2, the virus that causes COVID-19, by producing cytokines including type I and III interferons (IFNs) and proinflammatory factors such as IL6 and TNF. IFNs can limit SARS-CoV-2 replication but cytokine imbalance contributes to severe COVID-19. We studied...

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Publicado no:Sci Rep
Main Authors: Sampaio, Natalia G., Chauveau, Lise, Hertzog, Jonny, Bridgeman, Anne, Fowler, Gerissa, Moonen, Jurgen P., Dupont, Maeva, Russell, Rebecca A., Noerenberg, Marko, Rehwinkel, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8249624/
https://ncbi.nlm.nih.gov/pubmed/34211037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-92940-3
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