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Regulation and inhibition of the DNA sensor cGAS

Cell‐autonomous sensing of nucleic acids is essential for host defence against invading pathogens by inducing antiviral and inflammatory cytokines. cGAS has emerged in recent years as a non‐redundant DNA sensor important for detection of many viruses and bacteria. Upon binding to DNA, cGAS synthesis...

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Bibliografische gegevens
Gepubliceerd in:EMBO Rep
Hoofdauteurs: Hertzog, Jonny, Rehwinkel, Jan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7726805/
https://ncbi.nlm.nih.gov/pubmed/33155371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.202051345
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