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Regulation and inhibition of the DNA sensor cGAS
Cell‐autonomous sensing of nucleic acids is essential for host defence against invading pathogens by inducing antiviral and inflammatory cytokines. cGAS has emerged in recent years as a non‐redundant DNA sensor important for detection of many viruses and bacteria. Upon binding to DNA, cGAS synthesis...
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| Publicado no: | EMBO Rep |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7726805/ https://ncbi.nlm.nih.gov/pubmed/33155371 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.202051345 |
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