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Regulation and inhibition of the DNA sensor cGAS

Cell‐autonomous sensing of nucleic acids is essential for host defence against invading pathogens by inducing antiviral and inflammatory cytokines. cGAS has emerged in recent years as a non‐redundant DNA sensor important for detection of many viruses and bacteria. Upon binding to DNA, cGAS synthesis...

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Publicat a:EMBO Rep
Autors principals: Hertzog, Jonny, Rehwinkel, Jan
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7726805/
https://ncbi.nlm.nih.gov/pubmed/33155371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.202051345
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