Acetaldehyde exposure underlies functional defects in monocytes induced by excessive alcohol consumption

Increased intestinal permeability and hepatic macrophage activation by endotoxins are involved in alcohol-induced liver injury pathogenesis. Long-term alcohol exposure conversely induces endotoxin immune tolerance; however, the precise mechanism and reversibility are unclear. Seventy-two alcohol-dep...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Shiba, Shunsuke, Nakamoto, Nobuhiro, Chu, Po-Sung, Ojiro, Keisuke, Taniki, Nobuhito, Yamaguchi, Akihiro, Morikawa, Rei, Katayama, Tadashi, Yoshida, Aya, Aoki, Ryo, Teratani, Toshiaki, Suzuki, Takahiro, Miyamoto, Takeshi, Hara, Sachiko, Yokoyama, Akira, Kanai, Takanori
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2021
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8249592/
https://ncbi.nlm.nih.gov/pubmed/34211048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-93086-y
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