Plasmacytoid dendritic cells protect against immune-mediated acute liver injury via IL-35

Acute liver failure (ALF) is a life-threatening condition, and liver transplantation is the only therapeutic option. Although immune dysregulation is central to its pathogenesis, the precise mechanism remains unclear. Here, we show that the number of peripheral and hepatic plasmacytoid DCs (pDCs) de...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Koda, Yuzo, Nakamoto, Nobuhiro, Chu, Po-Sung, Ugamura, Aya, Mikami, Yohei, Teratani, Toshiaki, Tsujikawa, Hanako, Shiba, Shunsuke, Taniki, Nobuhito, Sujino, Tomohisa, Miyamoto, Kentaro, Suzuki, Takahiro, Yamaguchi, Akihiro, Morikawa, Rei, Sato, Katsuaki, Sakamoto, Michiie, Yoshimoto, Takayuki, Kanai, Takanori
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6668669/
https://ncbi.nlm.nih.gov/pubmed/31264967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI125863
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