Plasmacytoid dendritic cells protect against immune-mediated acute liver injury via IL-35

Acute liver failure (ALF) is a life-threatening condition, and liver transplantation is the only therapeutic option. Although immune dysregulation is central to its pathogenesis, the precise mechanism remains unclear. Here, we show that the number of peripheral and hepatic plasmacytoid DCs (pDCs) de...

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Bibliografski detalji
Izdano u:J Clin Invest
Glavni autori: Koda, Yuzo, Nakamoto, Nobuhiro, Chu, Po-Sung, Ugamura, Aya, Mikami, Yohei, Teratani, Toshiaki, Tsujikawa, Hanako, Shiba, Shunsuke, Taniki, Nobuhito, Sujino, Tomohisa, Miyamoto, Kentaro, Suzuki, Takahiro, Yamaguchi, Akihiro, Morikawa, Rei, Sato, Katsuaki, Sakamoto, Michiie, Yoshimoto, Takayuki, Kanai, Takanori
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2019
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6668669/
https://ncbi.nlm.nih.gov/pubmed/31264967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI125863
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