Bone marrow-derived macrophages distinct from tissue-resident macrophages play a pivotal role in Concanavalin A-induced murine liver injury via CCR9 axis

The fundamental mechanism how heterogeneous hepatic macrophage (Mφ) subsets fulfill diverse functions in health and disease has not been elucidated. We recently reported that CCR9(+) inflammatory Mφs play a critical role in the course of acute liver injury. To clarify the origin and differentiation...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Amiya, Takeru, Nakamoto, Nobuhiro, Chu, Po-sung, Teratani, Toshiaki, Nakajima, Hideaki, Fukuchi, Yumi, Taniki, Nobuhito, Yamaguchi, Akihiro, Shiba, Shunsuke, Miyake, Rei, Katayama, Tadashi, Ebinuma, Hirotoshi, Kanai, Takanori
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5057133/
https://ncbi.nlm.nih.gov/pubmed/27725760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35146
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