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Aggregation is a Context-Dependent Constraint on Protein Evolution

Solubility is a requirement for many cellular processes. Loss of solubility and aggregation can lead to the partial or complete abrogation of protein function. Thus, understanding the relationship between protein evolution and aggregation is an important goal. Here, we analysed two deep mutational s...

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書目詳細資料
發表在:Front Mol Biosci
Main Authors: Monti, Michele, Armaos, Alexandros, Fantini, Marco, Pastore, Annalisa, Tartaglia, Gian Gaetano
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2021
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8249573/
https://ncbi.nlm.nih.gov/pubmed/34222334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2021.678115
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