Detecting ALK Rearrangement with RT-PCR: A Reliable Approach Compared with Next-Generation Sequencing in Patients with NSCLC

BACKGROUND: Precise detection of anaplastic lymphoma kinase (ALK) rearrangement guides the application of ALK-targeted tyrosine kinase inhibitors (ALK-TKIs) in patients with non-small-cell lung cancer (NSCLC). Next-generation sequencing (NGS) has been widely used in clinics, but DNA-based NGS used t...

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Detalhes bibliográficos
Publicado no:Mol Diagn Ther
Main Authors: Kuang, Yukun, Xu, Peihang, Wang, Jiyu, Zheng, Yifan, Sun, Xue, Li, Zimu, Gan, RunJing, Li, Huixia, Guo, Yubiao, Yao, Fei, Zhu, Changbin, Ke, Zunfu, Tang, Kejing
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2021
Assuntos:
Original Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8249291/
https://ncbi.nlm.nih.gov/pubmed/34133003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40291-021-00532-8
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