Glomerular Filtration Rate in Asphyxiated Neonates Under Therapeutic Whole-Body Hypothermia, Quantified by Mannitol Clearance

BACKGROUND: Therapeutic hypothermia (TH) is an established intervention to improve the outcome of neonates with moderate-to-severe hypoxic-ischemic encephalopathy resulting from perinatal asphyxia. Despite this beneficial effect, TH may further affect drug elimination pathways such as the glomerular...

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Publicat a:Clin Pharmacokinet
Autors principals: Deferm, Neel, Annink, Kim V., Faelens, Ruben, Schroth, Michael, Maiwald, Christian A., Bakkali, Loubna el, van Bel, Frank, Benders, Manon J. N. L., van Weissenbruch, Mirjam M., Hagen, Anja, Smits, Anne, Annaert, Pieter, Franz, Axel R., Allegaert, Karel
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2021
Matèries:
Original Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8249265/
https://ncbi.nlm.nih.gov/pubmed/33611729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-021-00991-6
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