Functionally distinct POMC-expressing neuron subpopulations in hypothalamus revealed by intersectional targeting

Pro-opiomelanocortin (POMC)-expressing neurons in the arcuate nucleus of the hypothalamus represent key regulators of metabolic homeostasis. Electrophysiological and single-cell sequencing experiments have revealed a remarkable degree of heterogeneity of these neurons. However, the exact molecular b...

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Pubblicato in:Nat Neurosci
Autori principali: Biglari, Nasim, Gaziano, Isabella, Schumacher, Jonas, Radermacher, Jan, Paeger, Lars, Klemm, Paul, Chen, Weiyi, Corneliussen, Svenja, Wunderlich, Claudia M., Sue, Michael, Vollmar, Stefan, Klöckener, Tim, Sotelo-Hitschfeld, Tamara, Abbasloo, Amin, Edenhofer, Frank, Reimann, Frank, Gribble, Fiona M., Fenselau, Henning, Kloppenburg, Peter, Wunderlich, Frank T., Brüning, Jens C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group US 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8249241/
https://ncbi.nlm.nih.gov/pubmed/34002087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-021-00854-0
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