Energy imbalance alters Ca(2+) handling and excitability of POMC neurons

Satiety-signaling, pro-opiomelanocortin (POMC)-expressing neurons in the arcuate nucleus of the hypothalamus play a pivotal role in the regulation of energy homeostasis. Recent studies reported altered mitochondrial dynamics and decreased mitochondria- endoplasmic reticulum contacts in POMC neurons...

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Publicado en:eLife
Autores principales: Paeger, Lars, Pippow, Andreas, Hess, Simon, Paehler, Moritz, Klein, Andreas C, Husch, Andreas, Pouzat, Christophe, Brüning, Jens C, Kloppenburg, Peter
Formato: Artigo
Lenguaje:Inglês
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Neuroscience
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5538824/
https://ncbi.nlm.nih.gov/pubmed/28762947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.25641
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