Role of the transcriptional regulator SP140 in resistance to bacterial infections via repression of type I interferons

Type I interferons (IFNs) are essential for anti-viral immunity, but often impair protective immune responses during bacterial infections. An important question is how type I IFNs are strongly induced during viral infections, and yet are appropriately restrained during bacterial infections. The Supe...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:eLife
Egile Nagusiak: Ji, Daisy X, Witt, Kristen C, Kotov, Dmitri I, Margolis, Shally R, Louie, Alexander, Chevée, Victoria, Chen, Katherine J, Gaidt, Moritz M, Dhaliwal, Harmandeep S, Lee, Angus Y, Nishimura, Stephen L, Zamboni, Dario S, Kramnik, Igor, Portnoy, Daniel A, Darwin, K Heran, Vance, Russell E
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications, Ltd 2021
Gaiak:
Immunology and Inflammation
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8248984/
https://ncbi.nlm.nih.gov/pubmed/34151776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.67290
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