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Type I interferon-driven susceptibility to Mycobacterium tuberculosis is mediated by interleukin-1 receptor antagonist IL-1Ra

The bacterium Mycobacterium tuberculosis (Mtb) causes tuberculosis (TB) and is responsible for more human mortality than any other single pathogen(1). Progression to active disease occurs in only a fraction of infected individuals and is predicted by an elevated type I interferon (IFN) response(2-7)...

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Detalhes bibliográficos
Publicado no:Nat Microbiol
Main Authors: Ji, Daisy X., Yamashiro, Livia H., Chen, Katherine J., Mukaida, Naofumi, Kramnik, Igor, Darwin, K. Heran, Vance, Russell E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879852/
https://ncbi.nlm.nih.gov/pubmed/31611644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41564-019-0578-3
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