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Pharmacokinetics of Gepotidacin in Subjects With Normal Hepatic Function and Hepatic Impairment
Gepotidacin is a novel triazaacenaphthylene bacterial topoisomerase inhibitor. This phase 1 nonrandomized, open‐label, multicenter, 2‐part study evaluated the pharmacokinetics, safety, and tolerability of oral gepotidacin 1500 mg in 3 different hepatic settings (normal, moderate impairment, and seve...
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| Publicado no: | Clin Pharmacol Drug Dev |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8248074/ https://ncbi.nlm.nih.gov/pubmed/33450142 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpdd.913 |
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