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Pharmacokinetics of Gepotidacin in Renal Impairment

Gepotidacin is a novel triazaacenaphthylene bacterial topoisomerase inhibitor. In this phase 1, nonrandomized, open‐label, parallel‐group, multicenter, multipart study, the pharmacokinetics, safety, and tolerability of a single intravenous (IV) dose of gepotidacin 750 mg over 2 hours were evaluated...

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Detalhes bibliográficos
Publicado no:Clin Pharmacol Drug Dev
Main Authors: Hossain, Mohammad, Tiffany, Courtney, Raychaudhuri, Aparna, Nguyen, Dung, Tai, Guoying, Alcorn, Harry, Preston, Richard A., Marbury, Thomas, Dumont, Etienne
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7384084/
https://ncbi.nlm.nih.gov/pubmed/32429000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpdd.807
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