Impact of Acute Inflammation on Cytochromes P450 Activity Assessed by the Geneva Cocktail

Cytochromes P450 (CYP) are subject to important interindividual variability in their activity due to genetic and environmental factors and some diseases. Limited human data support the idea that inflammation downregulates CYP activities. Our study aimed to evaluate the impact of orthopedic surgery (...

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Bibliographische Detailangaben
Veröffentlicht in:Clin Pharmacol Ther
Hauptverfasser: Lenoir, Camille, Daali, Youssef, Rollason, Victoria, Curtin, François, Gloor, Yvonne, Bosilkovska, Marija, Walder, Bernhard, Gabay, Cem, Nissen, Michael John, Desmeules, Jules Alexandre, Hannouche, Didier, Samer, Caroline Flora
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2021
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8247903/
https://ncbi.nlm.nih.gov/pubmed/33341941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.2146
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