Impact of Acute Inflammation on Cytochromes P450 Activity Assessed by the Geneva Cocktail

Cytochromes P450 (CYP) are subject to important interindividual variability in their activity due to genetic and environmental factors and some diseases. Limited human data support the idea that inflammation downregulates CYP activities. Our study aimed to evaluate the impact of orthopedic surgery (...

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Detalhes bibliográficos
Publicado no:Clin Pharmacol Ther
Main Authors: Lenoir, Camille, Daali, Youssef, Rollason, Victoria, Curtin, François, Gloor, Yvonne, Bosilkovska, Marija, Walder, Bernhard, Gabay, Cem, Nissen, Michael John, Desmeules, Jules Alexandre, Hannouche, Didier, Samer, Caroline Flora
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8247903/
https://ncbi.nlm.nih.gov/pubmed/33341941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.2146
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