Sister chromatid cohesion defects are associated with chromosomal copy number heterogeneity in high hyperdiploid childhood acute lymphoblastic leukemia

High hyperdiploid acute lymphoblastic leukemia (ALL) is one of the most common malignancies in children. The main driver event of this disease is a nonrandom aneuploidy consisting of gains of whole chromosomes but without overt evidence of chromosomal instability (CIN). Here, we investigated the fre...

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Detalles Bibliográficos
Publicado en:Genes Chromosomes Cancer
Main Authors: Moura‐Castro, Larissa H., Peña‐Martínez, Pablo, Castor, Anders, Galeev, Roman, Larsson, Jonas, Järås, Marcus, Yang, Minjun, Paulsson, Kajsa
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley & Sons, Inc. 2021
Assuntos:
Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8247877/
https://ncbi.nlm.nih.gov/pubmed/33368842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.22933
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