Genetic and regulatory mechanism of susceptibility to high-hyperdiploid acute lymphoblastic leukaemia at 10q21.2

Despite high-hyperdiploid acute lymphoblastic leukaemia (HD-ALL) being the most common subgroup of paediatric ALL, its aetiology remains unknown. Genome-wide association studies have demonstrated association at 10q21.2. Here, we sought to determine how this region influences HD-ALL risk. We impute g...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Studd, James B., Vijayakrishnan, Jayaram, Yang, Minjun, Migliorini, Gabriele, Paulsson, Kajsa, Houlston, Richard S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5337971/
https://ncbi.nlm.nih.gov/pubmed/28256501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14616
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