Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia

To identify risk variants for childhood acute lymphoblastic leukemia (ALL) we conducted a genome-wide association study of 2 case-control series, analyzing the genotypes of 291,423 tagging SNP genotypes in a total of 907 ALL cases and 2,398 controls. We identified risk loci for ALL at 7p12.2 (IKZF1,...

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Detalhes bibliográficos
Publicado no:Nat Genet
Main Authors: Papaemmanuil, Elli, Hosking, Fay J, Vijayakrishnan, Jayaram, Price, Amy, Olver, Bianca, Sheridan, Eammon, Kinsey, Sally E, Lightfoot, Tracy, Roman, Eve, Irving, Julie A E, Allan, James M., Tomlinson, Ian P, Taylor, Malcolm, Greaves, Mel, Houlston, Richard S
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4915548/
https://ncbi.nlm.nih.gov/pubmed/19684604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.430
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