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Synthesis and Cell Growth Inhibitory Activity of Six Non‐glycosaminoglycan‐Type Heparin‐Analogue Trisaccharides

The design and synthesis of heparin mimetics with high anticancer activity but no anticoagulant activity is an important task in medicinal chemistry. Herein, we present the efficient synthesis of five Glc‐GlcA‐Glc‐sequenced and one Glc‐IdoA‐Glc‐sequenced non‐glycosaminoglycan, heparin‐related trisac...

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Detalhes bibliográficos
Publicado no:ChemMedChem
Main Authors: Lisztes, Erika, Mező, Erika, Demeter, Fruzsina, Horváth, Lilla, Bősze, Szilvia, István Tóth, Balázs, Borbás, Anikó, Herczeg, Mihály
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8247843/
https://ncbi.nlm.nih.gov/pubmed/33433040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.202000917
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