A disproportionate impact of G9a methyltransferase deficiency on the X chromosome

G9a is a histone methyltransferase responsible for the dimethylation of histone H3 at lysine 9 (H3K9me2). G9a plays key roles in transcriptional silencing of developmentally regulated genes, but its role in X-chromosome inactivation (XCI) has been under debate. Here, we uncover a female-specific fun...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Genes Dev
Autors principals: Szanto, Attila, Aguilar, Rodrigo, Kesner, Barry, Blum, Roy, Wang, Danni, Cifuentes-Rojas, Catherine, del Rosario, Brian C., Kis-Toth, Katalin, Lee, Jeannie T.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2021
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8247598/
https://ncbi.nlm.nih.gov/pubmed/34168040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.337592.120
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars