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Glucocorticoids suppress T cell function by upregulating microRNA 98

OBJECTIVES: To identify miRNA in human T cells that can explain known anti-inflammatory properties of steroids. MATERIALS AND METHODS: Activated human CD4(+) T cells from healthy donors were exposed to 1 μM of methylprednisolone in vitro were subjected to miRNA and mRNA microarray analysis and chang...

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Detalhes bibliográficos
Main Authors: Davis, Trevor E, Kis-Toth, Katalin, Szanto, Attila, Tsokos, George C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3713788/
https://ncbi.nlm.nih.gov/pubmed/23575983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.37966
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