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A disproportionate impact of G9a methyltransferase deficiency on the X chromosome
G9a is a histone methyltransferase responsible for the dimethylation of histone H3 at lysine 9 (H3K9me2). G9a plays key roles in transcriptional silencing of developmentally regulated genes, but its role in X-chromosome inactivation (XCI) has been under debate. Here, we uncover a female-specific fun...
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| 出版年: | Genes Dev |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Cold Spring Harbor Laboratory Press
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8247598/ https://ncbi.nlm.nih.gov/pubmed/34168040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.337592.120 |
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