Extrachromosomal DNA amplicons in antimalarial‐resistant Plasmodium falciparum

Extrachromosomal (ec) DNAs are genetic elements that exist separately from the genome. Since ecDNA can carry beneficial genes, they are a powerful adaptive mechanism in cancers and many pathogens. For the first time, we report ecDNA contributing to antimalarial resistance in Plasmodium falciparum, t...

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Publicado en:Mol Microbiol
Autores principales: McDaniels, Jennifer M., Huckaby, Adam C., Carter, Sabrina A., Lingeman, Sabrina, Francis, Audrey, Congdon, Molly, Santos, Webster, Rathod, Pradipsinh K., Guler, Jennifer L.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8246734/
https://ncbi.nlm.nih.gov/pubmed/33053232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.14624
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