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Novel Plasmodium falciparum metabolic network reconstruction identifies shifts associated with clinical antimalarial resistance

BACKGROUND: Malaria remains a major public health burden and resistance has emerged to every antimalarial on the market, including the frontline drug, artemisinin. Our limited understanding of Plasmodium biology hinders the elucidation of resistance mechanisms. In this regard, systems biology approa...

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Bibliografische gegevens
Gepubliceerd in:BMC Genomics
Hoofdauteurs: Carey, Maureen A., Papin, Jason A., Guler, Jennifer L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5518114/
https://ncbi.nlm.nih.gov/pubmed/28724354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-017-3905-1
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