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Novel Plasmodium falciparum metabolic network reconstruction identifies shifts associated with clinical antimalarial resistance

BACKGROUND: Malaria remains a major public health burden and resistance has emerged to every antimalarial on the market, including the frontline drug, artemisinin. Our limited understanding of Plasmodium biology hinders the elucidation of resistance mechanisms. In this regard, systems biology approa...

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Vydáno v:BMC Genomics
Hlavní autoři: Carey, Maureen A., Papin, Jason A., Guler, Jennifer L.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5518114/
https://ncbi.nlm.nih.gov/pubmed/28724354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-017-3905-1
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