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Antimalarial drug targets in Plasmodium falciparum predicted by stage-specific metabolic network analysis

BACKGROUND: Despite enormous efforts to combat malaria the disease still afflicts up to half a billion people each year of which more than one million die. Currently no approved vaccine is available and resistances to antimalarials are widely spread. Hence, new antimalarial drugs are urgently needed...

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Detalhes bibliográficos
Main Authors: Huthmacher, Carola, Hoppe, Andreas, Bulik, Sascha, Holzhütter, Hermann-Georg
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941759/
https://ncbi.nlm.nih.gov/pubmed/20807400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-4-120
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