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The Structural and Biochemical Characterization of UNC119B Cargo Binding and Release Mechanisms

[Image: see text] Two paralogs of the guanine dissociation inhibitor-like solubilizing factors UNC119, UNC119A and UNC119B, are present in the human genome. UNC119 binds to N-myristoylated proteins and masks the hydrophobic lipid from the hydrophilic cytosol, facilitating trafficking between differe...

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Bibliografiske detaljer
Udgivet i:Biochemistry
Main Authors: Yelland, Tamas, Garcia, Esther, Samarakoon, Youhani, Ismail, Shehab
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2021
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8246649/
https://ncbi.nlm.nih.gov/pubmed/34130453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.1c00251
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