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GTP-binding of ARL-3 is activated by ARL-13 as a GEF and stabilized by UNC-119
Primary cilia are sensory organelles indispensable for organogenesis and tissue pattern formation. Ciliopathy small GTPase ARLs are proposed as prominent ciliary switches, which when disrupted result in dysfunctional cilia, yet how ARLs are activated remain elusive. Here, we discover a novel small G...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4840320/ https://ncbi.nlm.nih.gov/pubmed/27102355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24534 |
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