Inducible hepatic expression of CREBH mitigates diet-induced obesity, insulin resistance, and hepatic steatosis in mice

Cyclic AMP-responsive element-binding protein H (CREBH encoded by Creb3l3) is a transcription factor that regulates the expression of genes that control lipid and glucose metabolism as well as inflammation. CREBH is upregulated in the liver under conditions of overnutrition, and mice globally lackin...

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Pubblicato in:J Biol Chem
Autori principali: Krumm, Christopher S., Xu, Xu, Bare, Curtis J., Holman, Corey D., Kersten, Sander, Dow, Lukas E., Lee, Ann-Hwee, Cohen, David E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2021
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8246594/
https://ncbi.nlm.nih.gov/pubmed/34023388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100815
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