Inducible hepatic expression of CREBH mitigates diet-induced obesity, insulin resistance, and hepatic steatosis in mice

Cyclic AMP-responsive element-binding protein H (CREBH encoded by Creb3l3) is a transcription factor that regulates the expression of genes that control lipid and glucose metabolism as well as inflammation. CREBH is upregulated in the liver under conditions of overnutrition, and mice globally lackin...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Krumm, Christopher S., Xu, Xu, Bare, Curtis J., Holman, Corey D., Kersten, Sander, Dow, Lukas E., Lee, Ann-Hwee, Cohen, David E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8246594/
https://ncbi.nlm.nih.gov/pubmed/34023388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100815
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