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Transcriptional activation of Fsp27 by the liver-enriched transcription factor CREBH promotes lipid droplet growth and hepatic steatosis

Fat-specific protein 27 (Fsp27) is a lipid droplet-associated protein that promotes lipid droplet (LD) growth and triglyceride (TG) storage in white adipocytes. Fsp27 is also highly expressed in the steatotic liver and contributes to TG accumulation. In this study, we discovered that the liver produ...

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Foilsithe in:Hepatology
Main Authors: Xu, Xu, Park, Jong-Gil, So, Jae-Seon, Lee, Ann-Hwee
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4329115/
https://ncbi.nlm.nih.gov/pubmed/25125366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.27371
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