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Biophysical properties of a tau seed

Pathogenesis of tauopathies involves conversion of tau monomer into pathological tau conformers that serve as templates to recruit native tau into growing assemblies. Small soluble tau seeds have been proposed to drive pathological tau assembly in vitro, in cells and in vivo. We have previously desc...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Hou, Zhiqiang, Chen, Dailu, Ryder, Bryan D., Joachimiak, Lukasz A.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8245522/
https://ncbi.nlm.nih.gov/pubmed/34193922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-93093-z
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