Enforced PGC-1α expression promotes CD8 T cell fitness, memory formation and antitumor immunity

Memory CD8 T cells can provide long-term protection against tumors, which depends on their enhanced proliferative capacity, self-renewal and unique metabolic rewiring to sustain cellular fitness. Specifically, memory CD8 T cells engage oxidative phosphorylation and fatty acid oxidation to fulfill th...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell Mol Immunol
Main Authors: Dumauthioz, Nina, Tschumi, Benjamin, Wenes, Mathias, Marti, Bastien, Wang, Haiping, Franco, Fabien, Li, Wenhui, Lopez-Mejia, Isabel C., Fajas, Lluis, Ho, Ping-Chih, Donda, Alena, Romero, Pedro, Zhang, Lianjun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8245409/
https://ncbi.nlm.nih.gov/pubmed/32055005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41423-020-0365-3
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados