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Alpha-Galactosylceramide/CD1d-Antibody Fusion Proteins Redirect Invariant Natural Killer T Cell Immunity to Solid Tumors and Promote Prolonged Therapeutic Responses

Major progress in cancer immunotherapies have been obtained by the use of tumor targeting strategies, in particular with the development of bi-functional fusion proteins such as ImmTacs or BiTes, which engage effector T cells for targeted elimination of tumor cells. Given the significance of invaria...

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Bibliografske podrobnosti
izdano v:Front Immunol
Main Authors: Zhang, Lianjun, Donda, Alena
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5672503/
https://ncbi.nlm.nih.gov/pubmed/29163493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01417
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