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Alpha-Galactosylceramide/CD1d-Antibody Fusion Proteins Redirect Invariant Natural Killer T Cell Immunity to Solid Tumors and Promote Prolonged Therapeutic Responses

Major progress in cancer immunotherapies have been obtained by the use of tumor targeting strategies, in particular with the development of bi-functional fusion proteins such as ImmTacs or BiTes, which engage effector T cells for targeted elimination of tumor cells. Given the significance of invaria...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Zhang, Lianjun, Donda, Alena
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5672503/
https://ncbi.nlm.nih.gov/pubmed/29163493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01417
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