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Alpha-Galactosylceramide/CD1d-Antibody Fusion Proteins Redirect Invariant Natural Killer T Cell Immunity to Solid Tumors and Promote Prolonged Therapeutic Responses

Major progress in cancer immunotherapies have been obtained by the use of tumor targeting strategies, in particular with the development of bi-functional fusion proteins such as ImmTacs or BiTes, which engage effector T cells for targeted elimination of tumor cells. Given the significance of invaria...

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Bibliografische gegevens
Gepubliceerd in:Front Immunol
Hoofdauteurs: Zhang, Lianjun, Donda, Alena
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5672503/
https://ncbi.nlm.nih.gov/pubmed/29163493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01417
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