Tip-Loaded Dissolvable Microneedle Arrays Effectively Deliver Polymer-Conjugated Antibody Inhibitors of Tumor-Necrosis-Factor-Alpha into Human Skin

Autoinflammatory skin diseases are characterized by a disequilibrium of cytokines in the local skin microenvironment, suggesting that local delivery of therapeutics, including anti-cytokine antibodies, may provide benefit without the unwanted off-target effects of systemically delivered therapies. R...

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Bibliografiske detaljer
Udgivet i:J Pharm Sci
Main Authors: Korkmaz, Emrullah, Friedrich, Emily E., Ramadan, M.H., Erdos, Geza, Mathers, Alicia R., Ozdoganlar, O. Burak, Washburn, Newell R., Falo, Louis D.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8245200/
https://ncbi.nlm.nih.gov/pubmed/27544434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xphs.2016.07.008
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