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Tip-Loaded Dissolvable Microneedle Arrays Effectively Deliver Polymer-Conjugated Antibody Inhibitors of Tumor-Necrosis-Factor-Alpha into Human Skin
Autoinflammatory skin diseases are characterized by a disequilibrium of cytokines in the local skin microenvironment, suggesting that local delivery of therapeutics, including anti-cytokine antibodies, may provide benefit without the unwanted off-target effects of systemically delivered therapies. R...
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| Gepubliceerd in: | J Pharm Sci |
|---|---|
| Hoofdauteurs: | , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2016
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8245200/ https://ncbi.nlm.nih.gov/pubmed/27544434 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xphs.2016.07.008 |
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