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Lacrimal gland budding requires PI3K-dependent suppression of EGF signaling
The patterning of epithelial buds is determined by the underlying signaling network. Here, we study the cross-talk between phosphoinositide 3-kinase (PI3K) and Ras signaling during lacrimal gland budding morphogenesis. Our results show that PI3K is activated by both the p85-mediated insulin-like gro...
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| Publicado en: | Sci Adv |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Association for the Advancement of Science
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8245041/ https://ncbi.nlm.nih.gov/pubmed/34193412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abf1068 |
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