In vitro engineering of a bone metastases model allows for study of the effects of antiandrogen therapies in advanced prostate cancer

While androgen-targeted therapies are routinely used in advanced prostate cancer (PCa), their effect is poorly understood in treating bone metastatic lesions and ultimately results in the development of metastatic castrate resistant prostate cancer (mCRPC). Here, we used an all-human microtissue-eng...

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Bibliografiske detaljer
Udgivet i:Sci Adv
Main Authors: Bock, Nathalie, Kryza, Thomas, Shokoohmand, Ali, Röhl, Joan, Ravichandran, Akhilandeshwari, Wille, Marie-Luise, Nelson, Colleen C., Hutmacher, Dietmar W., Clements, Judith A.
Format: Artigo
Sprog:Inglês
Udgivet: American Association for the Advancement of Science 2021
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8245033/
https://ncbi.nlm.nih.gov/pubmed/34193425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abg2564
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