In vitro engineering of a bone metastases model allows for study of the effects of antiandrogen therapies in advanced prostate cancer

While androgen-targeted therapies are routinely used in advanced prostate cancer (PCa), their effect is poorly understood in treating bone metastatic lesions and ultimately results in the development of metastatic castrate resistant prostate cancer (mCRPC). Here, we used an all-human microtissue-eng...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Bock, Nathalie, Kryza, Thomas, Shokoohmand, Ali, Röhl, Joan, Ravichandran, Akhilandeshwari, Wille, Marie-Luise, Nelson, Colleen C., Hutmacher, Dietmar W., Clements, Judith A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2021
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8245033/
https://ncbi.nlm.nih.gov/pubmed/34193425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abg2564
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