Regulatory T Cells Increase After rh-MOG Stimulation in Non-Relapsing but Decrease in Relapsing MOG Antibody-Associated Disease at Onset in Children

BACKGROUND: Myelin oligodendrocytes glycoprotein (MOG) antibody-associated disease (MOGAD) represent 25% of pediatric acquired demyelinating syndrome (ADS); 40% of them may relapse, mimicking multiple sclerosis (MS), a recurrent and neurodegenerative ADS, which is MOG-Abs negative. AIMS: To identify...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Horellou, Philippe, de Chalus, Aliénor, Giorgi, Laetitia, Leroy, Carole, Chrétien, Pascale, Hacein-Bey-Abina, Salima, Bourgeois, Christine, Mariette, Xavier, Serguera, Ché, Le Grand, Roger, Deiva, Kumaran
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8243969/
https://ncbi.nlm.nih.gov/pubmed/34220827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.679770
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