Effect of ARTEMIS (DCLRE1C) deficiency and microinjection timing on editing efficiency during somatic cell nuclear transfer and in vitro fertilization using the CRISPR/Cas9 system

The ability to efficiently introduce site-specific genetic modifications to the mammalian genome has been dramatically improved with the use of the CRISPR/Cas9 system. CRISPR/Cas9 is a powerful tool used to generate genetic modifications by causing double-strand breaks (DSBs) in DNA. Artemis (ART; a...

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Bibliografski detalji
Izdano u:Theriogenology
Glavni autori: Li, Yunsheng, Adur, Malavika K., Wang, Wei, Schultz, R. Blythe, Hale, Benjamin, Wierson, Wesley, Charley, Sara E., McGrail, Maura, Essner, Jeffrey, Tuggle, Christopher K., Ross, Jason W.
Format: Artigo
Jezik:Inglês
Izdano: 2021
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8243557/
https://ncbi.nlm.nih.gov/pubmed/34004455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.theriogenology.2021.04.003
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