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Inhibition of germinal vesicle breakdown using IBMX increases microRNA-21 in the porcine oocyte

BACKGROUND: Germinal vesicle breakdown (GVBD) occurs during oocyte meiotic maturation, a period when transcriptional processes are virtually inactive. Thus, the maturing oocyte is reliant on processes such as post-transcriptional gene regulation (PTGR) to regulate the mRNA and protein repertoire. Mi...

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Veröffentlicht in:Reprod Biol Endocrinol
Hauptverfasser: Hale, Benjamin J., Li, Yunsheng, Adur, Malavika K., Ross, Jason W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7212575/
https://ncbi.nlm.nih.gov/pubmed/32393269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12958-020-00603-1
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