ZP3 is Required for Germinal Vesicle Breakdown in Mouse Oocyte Meiosis

ZP3 is a principal component of the zona pellucida (ZP) of mammalian oocytes and is essential for normal fertility, and knockout of ZP3 causes complete infertility. ZP3 promotes fertilization by recognizing sperm binding and activating the acrosome reaction; however, additional cellular roles for ZP...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Gao, Lei-Lei, Zhou, Chun-Xiang, Zhang, Xiao-Lan, Liu, Peng, Jin, Zhen, Zhu, Gang-Yi, Ma, Yang, Li, Jing, Yang, Zhi-Xia, Zhang, Dong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5286536/
https://ncbi.nlm.nih.gov/pubmed/28145526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41272
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