The histone reader PHF7 cooperates with the SWI/SNF complex at cardiac super enhancers to promote direct reprogramming

Direct cardiac reprogramming of fibroblasts to cardiomyocytes presents an attractive therapeutic strategy to restore cardiac function following injury. Cardiac reprogramming was initially achieved through overexpression of the transcription factors Gata4, Mef2c and Tbx5; later, Hand2 and Akt1 were f...

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Detaylı Bibliyografya
Yayımlandı:Nat Cell Biol
Asıl Yazarlar: Garry, Glynnis A., Bezprozvannaya, Svetlana, Chen, Kenian, Zhou, Huanyu, Hashimoto, Hisayuki, Morales, Maria Gabriela, Liu, Ning, Bassel-Duby, Rhonda, Olson, Eric N.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2021
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8243412/
https://ncbi.nlm.nih.gov/pubmed/33941892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-021-00668-z
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