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Development of a Physiologically Based Pharmacokinetic Model for Prediction of Ethanol Concentration-Time Profile in Different Organs
AIMS: A physiologically based pharmacokinetic (PBPK) modeling approach was used to simulate the concentration-time profile of ethanol (EtOH) in stomach, duodenum, plasma and other tissues upon consumption of beer and whiskey under fasted and fed conditions. METHODS: A full PBPK model was developed f...
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| Publicado no: | Alcohol Alcohol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8243283/ https://ncbi.nlm.nih.gov/pubmed/33316031 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/alcalc/agaa129 |
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