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Altering ethanol pharmacokinetics to treat alcohol use disorder: can you teach an old dog new tricks?

Disulfiram was the first pharmacotherapy approved to treat alcohol use disorder (AUD) in the 1950s. Disulfiram alters ethanol pharmacokinetics (PK) and causes uncomfortable reactions (e.g.: headache, tachycardia, nausea, flushing and hypotension) when alcohol is consumed. Subsequently, a better unde...

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Detalhes bibliográficos
Publicado no:J Psychopharmacol
Main Authors: Haass-Koffler, Carolina L., Akhlaghi, Fatemeh, Swift, Robert M., Leggio, Lorenzo
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768306/
https://ncbi.nlm.nih.gov/pubmed/28093021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0269881116684338
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