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Altering ethanol pharmacokinetics to treat alcohol use disorder: can you teach an old dog new tricks?
Disulfiram was the first pharmacotherapy approved to treat alcohol use disorder (AUD) in the 1950s. Disulfiram alters ethanol pharmacokinetics (PK) and causes uncomfortable reactions (e.g.: headache, tachycardia, nausea, flushing and hypotension) when alcohol is consumed. Subsequently, a better unde...
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| Veröffentlicht in: | J Psychopharmacol |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5768306/ https://ncbi.nlm.nih.gov/pubmed/28093021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0269881116684338 |
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